Vibromulino MM 400

Informazioni tecniche (2)

Reports applicativi (23)

  • Bigger is NOT Better – Preparazione del campione nell’industria farmaceutica

    Introduzione: La tendenza è quella di avere quantità di campione dalle dimensioni sempre minori e controllate ma comunque rappresentative.

    Nell’analisi dei materiali solidi certamente non si applica il detto popolare “più grande è meglio”. L’obiettivo è produrre particelle sufficientemente piccole da soddisfare i requisiti delle analisi, garantendo nel contempo una rappresentazione accurata del materiale originale.
    Le “particelle” d’interesse per l’analista vanno generalmente da 10 µm a 2 mm, ma in molte applicazioni sono necessarie granulometrie ancora più fini.
    Un esempio sono i principi attivi, dove è necessario operare nel range dei submicron. Infine, per l’estrazione di DNA ed RNA, la tecnica della lisi cellulare è già ben consolidata.
  • Cosa rivelano i capelli

    Il rilevamento di droghe e farmaci illegali è importante in settori quali la scienza forense, il traffico o competizioni sportive. Sostanze chimiche si possono riscontrare nel sangue, nella saliva, nelle urine e nel capello, quest’ultimo possiede il vantaggio di memorizzare le sostanze per un periodo più o meno lungo, a seconda della sua lunghezza. Oltre al rilevamento delle droghe, i capelli sono utilizzati anche per le analisi del DNA.
  • White Paper: Cryogenic Preparation of Sample Materials

    A solid sample material should always be sufficiently prepared by size reduction and homogenization before it is subjected to chemical or physical analysis. Care should be taken that the analysis sample fully represents the original material and that the sample preparation process is carried out reproducibly. Only then are meaningful results guaranteed. Most sample materials can be reduced to the required analytical fineness at room temperature by choosing a mill with a suitable size reduction principle (impact, pressure, friction, shearing, cutting).
  • Pesticide analsis of soil - not without sample preparation

    The use of pesticides in agriculture makes it possible to plant extensive mono cultures and often leads to substantial yield increases of food and feed crops. Demand and application have grown steadily over the years, leading to increased contamination of the soil due to the toxic nature of pesticides. Soils save the toxins and their decomposition products so that wildlife is also affected by them. Among the undesired side effects are damages to useful plants and insects like bees. The wind carries pesticides to uncontaminated areas such as fields used for organic farming. Rain also transports the chemicals away from their original area of application to waters and groundwater. Although in most cases the limit values for particular pesticides and their decomposition products are not exceeded, the cumulative effect on humans and animals has not been thoroughly investigated so far. The possible accumulation of pesticides in the food chain could be a source of health hazards; therefore strict quality control of soils is indispensable.
  • The effect of grinding tools on metal contamination

    Reliable and accurate analysis results can only be guaranteed by reproducible sample preparation. This consists of transforming a laboratory sample into a representative part sample with homogeneous analytical fineness. Retsch offers a comprehensive range of the most modern mills and crushers for coarse, fine and ultra-fine size reduction of almost any material. The product range also comprises a wide choice of grinding tools and accessories which helps to ensure contamination-free preparation of a great variety of sample materials.
    The selection of the correct grinding tool depends on the sample material and the subsequent method of analysis. Different grinding tools have different characteristics, such as required energy input, hardness or wear-resistance.
  • Recycled glass - a valuable resource

    Today, recycled glass is the most important resource for the glass industry. The processed glass can be reintroduced to the melting process any number of times and made into new products. In Germany, currently up to 95 % of recycled glass is used for producing glass, which has various advantages: energy saving, less consumption of primary raw materials (such as lime and silica sand) and the reduction of landfill costs for waste glass.
  • Sample preparation for pesticide residue analysis with the QuEChERS method

    The so-called QuEChERS method (“quick, easy, cheap, effective, rugged and safe”) was developed by Michelangelo Anastassiades (Chemical and Veterinary Investigation Office CVUA, Stuttgart, Germany) to make sample preparation to pesticide residue analysis more efficient. It basically consists of three steps: Homogenization – Extraction – Analysis. Test series have proved that the analysis results obtained with the QuEChERS method can easily compare with more common methods, such as DFG S19. Various RETSCH instruments are used for the sample preparation process.
  • As fine as necessary

    A variety of methods can be used to analyze solid materials. What they all have in common is the necessity to use a representative, homogeneous analysis sample which needs to have a particular fineness, depending on the analytical method used. The size reduction and homogenization of solids is usually carried out with laboratory crushers and grinders.
  • Representative Analysis Results Require Adequate Sample Preparation

    A faultless and comparable analysis is closely linked to an accurate sample handling. Only a sample representative of the initial material can provide meaningful analysis results. Rotating dividers and rotary tube dividers are an important means to ensure the representativeness of a sample and thus the reproducibility of the analysis. Correct sample handling consequently minimizes the probability of a production stop due to incorrect analysis results. Thus correct sample handling is the key to effective quality control.
  • What Hair Reveals

    The detection of illegal drugs and pharmaceuticals plays a role in various fields, for example in forensic science, road traffic accidents, in competitive sports or at the workplace. Chemical substances can be detected in blood, saliva, urine and in hair. Hair has the great advantage of storing the substances for a long period, which means that detection is still possible several months after consumption of the drug. In addition to the detection of drugs, hair samples are also used for DNA analysis as well as for the analysis of heavy metals and minerals.
  • Rapid and efficient disruption of yeast cells with the Mixer Mill MM 400

    Cell disruption of bacteria, yeast, filamentous fungi or microalgae is a standard procedure in basic biological research, applied biotechnology or medical research to get access to nucleic acids (DNA, RNA) or cell proteins. For the isolation of DNA or RNA usually less than 1 ml of cell material is needed. For the extraction of proteins, however, larger amounts of cell suspension are required. A very efficient method of cell disruption is the co called “bead beating” where cells in suspension are mechanically disrupted by glass beads in single-use reaction vials.
  • Toxic analyses of biological samples

    Cryogenic grinding facilitates the preparation of animal samples
  • Representative sample preparation for XRF analysis

    Preparing homogeneous samples by milling
  • Efficient Grinding at –196 °C

    RETSCH’s New CryoMill for Safe and Reproducible Grinding with Liquid Nitrogen
  • Tracking Down Fake Cashmere

    Cashmere wool is the best known precious wool. It is won from the cashmere goat which originates from the high mountain region of the same name. Due to its properties such as softness and warmth, cashmere wool gains more and more popularity in the manufacture of clothing. Genuine cashmere is won solely from the goat’s downy hair and must possess a certain hair structure with an exactly defined length and thickness.
  • Sick with Dolls

    Traces of Heavy Metals in Toys
  • Green Chemistry in the Lab

    Mechanochemistry is a very effective method to carry out syntheses without solvents and by-products. The technical literature describes a great number of reactions where a conversion of 100% is achieved. A precondition for the establishment of mechanochemistry in the industrial sector is the availability of suitable laboratory mills. A decisive factor is that – similar to conventional preparative chemistry – ambient parameters such as pressure and temperature can be documented and monitored. The Planetary Ball Mills and Mixer Mills from Retsch fulfill these requirements.
  • Size reduction within the context of sample preparation

    In general “size reduction” is taken to mean the disintegration of solid substances by mechanical forces without altering their state.
  • Making Whole Cell Extract of Saccharomyces cerevisiae

    Preparation at the Courtesy of the Staley Lab at the University of Chicago
  • Sample Preparation of Solid Materials for the XRF-analysis

    X-Ray fluorescence is one of the most versatile methods to determine elements in a sample. The material is exposed to x-rays that cause each element to emit its own unique fluorescent x-ray. The subsequent analysis of the results is based on comparisons to standard samples with given chemical composition.
  • Bigger is not Better

    There is a trend towards smaller samples that have more controlled particle size and yet remain representative of the material being analyzed.
  • Cryogenic disruption of yeast cells

    The MM 301 can be used for cell disruption applications. In this case, yeast cells were embrittled with liquid nitrogen.

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